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1

A metabolic network approach for the identification and prioritization of antimicrobial drug targets

Arvind K. Chavali, Kevin M. D’Auria, Erik L. Hewlett, Richard D. Pearson, Jason A. Papin

Journal:

Trends in Microbiology

Year:

2012

Language:

english

File:

PDF, 608 KB

english, 2012

2

Transforming growth factor β enhances parathyroid hormone stimulation of adenylate cyclase in clonal osteoblast-like cells

Gloria E. Gutierrez, Gregory R. Mundy, Michael S. Katz, David R. Manning, Erik L. Hewlett

Journal:

Journal of Cellular Physiology

Year:

1990

Language:

english

File:

PDF, 1.04 MB

english, 1990

3

In vivo suppression of delayed hypersensitivity by thiabendazole and diethylcarbamazine

Erik L. Hewlett, Osama Y. Hamid, Juanita Ruffier, Adel A.F. Mahmoud

Journal:

Immunopharmacology

Year:

1981

Language:

english

File:

PDF, 432 KB

english, 1981

4

Mechanism of association of adenylate cyclase toxin with the surface of Bordetella pertussis: a role for toxin–filamentous haemagglutinin interaction

Franca R. Zaretzky, Mary C. Gray, Erik L. Hewlett

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 137 KB

english, 2002

5

Systems analysis of the transcriptional response of human ileocecal epithelial cells toClostridium difficiletoxins and effects on cell cycle control

Kevin M D’Auria, Gina M Donato, Mary C Gray, Glynis L Kolling, Cirle A Warren, Lauren M Cave, Michael D Solga, Joanne A Lannigan, Jason A Papin, Erik L Hewlett

Journal:

BMC Systems Biology

Year:

2012

Language:

english

File:

PDF, 321 KB

english, 2012

6

Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis: more than just making cyclic AMP!

Erik L. Hewlett, Gina M. Donato, Mary C. Gray

Journal:

Molecular Microbiology

Year:

2006

Language:

english

File:

PDF, 858 KB

english, 2006

7

Bordetella pertussis adenylate cyclase toxin (ACT) induces cyclooxygenase-2 (COX-2) in murine macrophages and is facilitated by ACT interaction with CD11b/CD18 (Mac-1)

Darren J. Perkins, Mary C. Gray, Erik L. Hewlett, Stefanie N. Vogel

Journal:

Molecular Microbiology

Year:

2007

Language:

english

File:

PDF, 469 KB

english, 2007

8

Cell cycle arrest induced by the bacterial adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis

Mary C. Gray, Erik L. Hewlett

Journal:

Cellular Microbiology

Year:

2011

Language:

english

File:

PDF, 1.00 MB

english, 2011

9

Antibodies to Bordetella pertussis adenylate cyclase toxin in neonatal and maternal sera

Juan L. Arciniega, Erik L. Hewlett, Kathryn M. Edwards, Drusilla L. Burns

Journal:

FEMS Immunology & Medical Microbiology

Year:

1993

Language:

english

File:

PDF, 369 KB

english, 1993

10

Toxins of Vibrio cholerae and Escherichia coli stimulate adenyl cyclase in rat fat cells

HEWLETT, ERIK L., GUERRANT, RICHARD L., EVANS, DOYLE J., GREENOUGH, WILLIAM B.

Journal:

Year:

1974

File:

PDF, 481 KB

1974

11

Adenylate cyclase in striatal cholinergic interneurons regulates acetylcholine release

Ivan S. Login, Erik L. Hewlett

Journal:

Year:

1996

Language:

english

File:

PDF, 513 KB

english, 1996

12

Delivery of Bordetella pertussis adenylate cyclase toxin to target cells via outer membrane vesicles

Gina M. Donato, Cynthia S. Goldsmith, Christopher D. Paddock, Joshua C. Eby, Mary C. Gray, Erik L. Hewlett

Journal:

Year:

2012

Language:

english

File:

PDF, 937 KB

english, 2012

13

Spurious Protein Activators of Bordetella pertussis Adenylate Cyclase

Alan R. GOLDHAMMER, J. WOLFF, G. HOPE COOK, Steven A. BERKOWITZ, Claude B. KLEE, C. R. MANCLARK, Erik L. HEWLETT

Journal:

Year:

1981

Language:

english

File:

PDF, 572 KB

english, 1981

14

Structural Consequences of Divalent Metal Binding by the Adenylyl Cyclase Toxin of Bordetella pertussis

Christopher R. Rhodes, Mary C. Gray, Justin M. Watson, Tara L. Muratore, Sharon B. Kim, Erik L. Hewlett, Charles M. Grisham

Journal:

Archives of Biochemistry and Biophysics

Year:

2001

Language:

english

File:

PDF, 405 KB

english, 2001

15

Inhibition of adenylate cyclase from luteinized rat ovary by monovalent cations: Roles of the stimulatory guanine nucleotide-binding regulatory component and stimulatory hormone receptor

Lata R. Joshi, Sarah R. Boland, Erik L. Hewlett, Michael S. Katz

Journal:

Archives of Biochemistry and Biophysics

Year:

1988

Language:

english

File:

PDF, 1.30 MB

english, 1988

16

Requirement for both choleragen and pertussis toxin to obtain maximal activation of adenylate cyclase in cultured cells

Judith A. Hsia, Joel Moss, Erik L. Hewlett, Martha Vaughan

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 387 KB

english, 1984

17

Evidence for a functionally active inhibitory guanine nucleotide-binding regulatory protein in the swine ovary

Johannes D. Veldhuis, Erik L. Hewlett

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 651 KB

english, 1985

18

Tropical diseases in North America

Richard D. Pearson, Erik L. Hewlett, Richard L. Guerrant

Journal:

Disease-a-Month

Year:

1984

Language:

english

File:

PDF, 3.58 MB

english, 1984

19

Hemolytic activity of adenylate cyclase toxin fromBordetella pertussis

Ingrid E. Ehrmann, Mary C. Gray, Valery M. Gordon, Lloyd S. Gray, Erik L. Hewlett

Journal:

Year:

1991

Language:

english

File:

PDF, 402 KB

english, 1991

20

Enzymatic activity of adenylate cyclase toxin from Bordetella pertussis is not required for hemolysis

Ingrid E. Ehrmann, Alison A. Weiss, M.S. Goodwin, Mary C. Gray, Eileen Barry, Erik L. Hewlett

Journal:

Year:

1992

Language:

english

File:

PDF, 650 KB

english, 1992

21

Meiotic resumption in response to luteinizing hormone is independent of a Gi family G protein or calcium in the mouse oocyte

Lisa M. Mehlmann, Rebecca R. Kalinowski, Lavinia F. Ross, Albert F. Parlow, Erik L. Hewlett, Laurinda A. Jaffe

Journal:

Developmental Biology

Year:

2006

Language:

english

File:

PDF, 592 KB

english, 2006

22

Effects of pertussis toxin-catalyzed ADP-ribosylation on interactions of transducin and the inhibitory GTP-binding protein of adenylate cyclase with guanyl nucleotides

Paola Bruni, Erik L. Hewlett, Joel Moss

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 454 KB

english, 1985

23

Protective antibodies in pertussis

James D. Cherry, Erik L. Hewlett, Edward A. Mortimer Jr.

Journal:

The Journal of Pediatrics

Year:

1990

Language:

english

File:

PDF, 105 KB

english, 1990

24

Toxic shock syndrome: Clinicopathologic findings in a fatal case

Fadi W. Abdul-Karim, Michael M. Lederman, John R. Carter, Erik L. Hewlett, Arthur J. Newman, Bruce M. Greene

Journal:

Human Pathology

Year:

1981

Language:

english

File:

PDF, 2.13 MB

english, 1981

25

[Part 1: Biological Sciences] || Promotion of Lipolysis in Rat Adipocytes by Pertussis Toxin: Reversal of Endogenous Inhibition

Leann Olansky, Gwendolyn A. Myers, Stephen L. Pohl and Erik L. Hewlett

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.03 MB

english, 1983

26

Pertussis Toxin is Required for Pertussis Vaccine Encephalopathy

Lawrence Steinman, Alison Weiss, Nancy Adelman, Mae Lim, Richard Zuniga, John Oehlert, Erik Hewlett and Stanley Falkow

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 722 KB

english, 1985

27

Pertussis Toxin or Phorbol 12-myristate 13-acetate Can Distinguish between Epidermal Growth Factor- and Angiotensin-Stimulated Signals in Hepatocytes

Randolph M. Johnson, Patricia A. Connelly, Robert B. Sisk, Bonnie F. Pobiner, Erik L. Hewlett and James C. Garrison

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.04 MB

english, 1986

28

Pertussis — Not Just for Kids

Hewlett, Erik L., Edwards, Kathryn M.

Journal:

Boston Medical and Surgical Journal

Year:

2005

Language:

english

File:

PDF, 177 KB

english, 2005

29

Stimulation of the thiol-dependent ADP-ribosyltransferase and NAD glycohydrolase activities of Bordetella pertussis toxin by adenine nucleotides, phospholipids, and detergents

Moss, Joel, Stanley, Sally J., Watkins, Paul A., Burns, Drusilla L., Manclark, Charles R., Kaslow, Harvey R., Hewlett, Erik L.

Journal:

Year:

1986

Language:

english

File:

PDF, 1.77 MB

english, 1986

30

Effect of Temperature and Host Factors on the Activities of Pertussis Toxin and Bordetella Adenylate Cyclase

Murayama, Toshihiko, Hewlett, Erik L., Maloney, Nancy J., Justice, John M., Moss, Joel

Journal:

Year:

1994

Language:

english

File:

PDF, 914 KB

english, 1994

31

Pertussis Toxin-Catalyzed ADP-Ribosylation: Effects on the Coupling of Inhibitory Receptors to the Adenylate Cyclase System

Moss, Joel, Bruni, Paola, Hsia, Judith A., Tsai, Su-Chen, Watkins, Paul A., Halpern, Jane L., Burns, Drusilla L., Kanaho, Yasunori, Chang, Patrick P., Hewlett, Erik L., Vaughan, Martha

Journal:

Journal of Receptor and Signal Transduction Research

Year:

1984

Language:

english

File:

PDF, 1.87 MB

english, 1984

32

Protection against Infection with Giardia muris by Milk Containing Antibody to Giardia

John S. Andrews Jr. and Erik L. Hewlett

Journal:

The Journal of Infectious Diseases

Year:

1981

Language:

english

File:

PDF, 840 KB

english, 1981

33

Experimental Infection of Mongrel Dogs with Giardia lamblia Cysts and Cultured Trophozoites

Erik L. Hewlett, John S. Andrews Jr., Juanita Ruffier and Frank W. Schaefer III

Journal:

The Journal of Infectious Diseases

Year:

1982

Language:

english

File:

PDF, 792 KB

english, 1982

34

Supplement 2. Pertussis in Adults: Epidemiology, Signs, Symptoms, and Implications for Vaccination || A Commentary on the Pathogenesis of Pertussis

Erik L. Hewlett

Journal:

Clinical Infectious Diseases

Year:

1999

Language:

english

File:

PDF, 266 KB

english, 1999

35

Selective Primary Health Care: Strategies for Control of Disease in the Developing World. XVIII. Pertussis and Diphtheria

Erik L. Hewlett

Journal:

Reviews of Infectious Diseases

Year:

1985

Language:

english

File:

PDF, 298 KB

english, 1985

36

Pertussis Toxin and Extracytoplasmic Adenylate Cyclase as Virulence Factors of Bordetella pertussis

Alison A. Weiss, Erik L. Hewlett, Gwendolyn A. Myers and Stanley Falkow

Journal:

The Journal of Infectious Diseases

Year:

1984

Language:

english

File:

PDF, 564 KB

english, 1984

37

Giardia lamblia Infection of Suckling Mice

David R. Hill, Richard L. Guerrant, Richard D. Pearson and Erik L. Hewlett

Journal:

The Journal of Infectious Diseases

Year:

1983

Language:

english

File:

PDF, 1.02 MB

english, 1983

38

Contribution of Bordetella Filamentous Hemagglutinin and Adenylate Cyclase Toxin to Suppression and Evasion of Interleukin-17-Mediated Inflammation

Henderson, Michael W., Inatsuka, Carol S., Sheets, Amanda J., Williams, Corinne L., Benaron, David J., Donato, Gina M., Gray, Mary C., Hewlett, Erik L., Cotter, Peggy A., Bäumler, A. J.

Journal:

Infection and Immunity

Year:

2012

Language:

english

File:

PDF, 3.20 MB

english, 2012

39

Whole-Genome Sequencing in Outbreak Analysis

Gilchrist, Carol A., Turner, Stephen D., Riley, Margaret F., Petri, William A., Hewlett, Erik L.

Journal:

Clinical Microbiology Reviews

Year:

2015

Language:

english

File:

PDF, 1.43 MB

english, 2015

40

Differences in Purinergic Amplification of Osmotic Cell Lysis by the Pore-Forming RTX Toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the Role of Pore Size

Masin, Jiri, Fiser, Radovan, Linhartova, Irena, Osicka, Radim, Bumba, Ladislav, Hewlett, Erik L., Benz, Roland, Sebo, Peter, Blanke, S. R.

Journal:

Infection and Immunity

Year:

2013

Language:

english

File:

PDF, 3.46 MB

english, 2013

41

A Commentary on the Pathogenesis of Pertussis

Hewlett, Erik L.

Journal:

Clinical Infectious Diseases

Year:

1999

Language:

english

File:

PDF, 105 KB

english, 1999

42

“ANTIGONADAL” ACTIVITY OF THE NEUROHYPOPHYSIAL HORMONES IN CULTURED RAT TESTICULAR CELLS: ABOLITION BY PERTUSSIS TOXIN

ADASHI, ELI Y., RESNICK, CAROL E., CRONIN, J., HEWLETT, ERIK L.

Journal:

Year:

1984

Language:

english

File:

PDF, 390 KB

english, 1984

43

High temporal resolution of glucosyltransferase dependent and independent effects of Clostridium difficile toxins across multiple cell types

D’Auria, Kevin M, Bloom, Meghan J, Reyes, Yesenia, Gray, Mary C, van Opstal, Edward J, Papin, Jason A, Hewlett, Erik L

Journal:

BMC Microbiology

Year:

2015

Language:

english

File:

PDF, 1.84 MB

english, 2015

44

Pertussis Toxin Blocks the Somatostatin-Induced Inhibition of Growth Hormone Release and Adenosine 3′,5′ -Monophosphate Accumulation *

CRONIN, MICHAEL J., ROGOL, ALAN D., MYERS, GWEN A., HEWLETT, ERIK L.

Journal:

Year:

1983

Language:

english

File:

PDF, 885 KB

english, 1983

45

Human Pancreatic Tumor Growth Hormone (GH)-Releasing Factor and Cyclic Adenosine 3′,5′-Monophosphate Evoke GH Release from Anterior Pituitary Cells: The Effects of Pertussis Toxin, Cholera Toxin, Forskolin, and Cycloheximide *

CRONIN, MICHAEL J., HEWLETT, ERIK L., EVANS, WILLIAM S., THORNER, MICHAEL O., ROGOL, ALAN D.

Journal:

Year:

1984

Language:

english

File:

PDF, 1.06 MB

english, 1984

46

A Putative Mediator of Insulin Action Which Inhibits Adenylate Cyclase and Adenosine 3′,5′-Monophosphate- Dependent Protein Kinase: Partial Purificaton from Rat Liver: Site and Kinetic Mechanism of Action*

MALCHOFF, CARL D., HUANG, LAURA, GILLESPIE, NAN, PALASI, CARLOS VILLAR, SCHWARTZ, CHARLES F. W., CHENG, RANG, HEWLETT, ERIK L., LARNER, JOSEPH

Journal:

Year:

1987

Language:

english

File:

PDF, 1.37 MB

english, 1987

47

Actions of Cyclic Adenosine Monophosphate on the Cytodifferentiation of Ovarian Cells: Studies in Cultured Swine Granulosa Cells Using a Novel Exogenous Adenylate Cyclase from Bordetella pertussis

Veldhuis, Johannes D., Rodgers, Raymond J., Hewlett, Erik L., Azimi, Paula, Garmey, James, Gray, Mary, Juchter, Diana, Wait, Annabel

Journal:

Molecular Endocrinology

Year:

1988

Language:

english

File:

PDF, 898 KB

english, 1988

48

The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies.

Wang, Xianzhe, Gray, Mary C., Hewlett, Erik L., Maynard, Jennifer A.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 47 KB

english, 2015

49

Human Serologic Response to Envelope-Associated Proteins and Adenylate Cyclase Toxin of Bordetella pertussis

Juan L. Arciniega, Erik L. Hewlett, Frederick D. Johnson, Adamadia Deforest, Steven G. F. Wassilak, Ida M. Onorato, Charles R. Manclark and Drusilla L. Burns

Journal:

The Journal of Infectious Diseases

Year:

1991

Language:

english

File:

PDF, 1.72 MB

english, 1991

50

Protein kinase A translocation and insulin secretion in pancreatic β-cells: studies with adenylate cyclase toxin from Bordetella pertussis

GAO, Zhiyong, YOUNG, Robert A., TRUCCO, Matteo M., GREENE, Scott R., HEWLETT, Erik L., MATSCHINSKY, Franz M., WOLF, Bryan A.

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 374 KB

english, 2002